Molecular epidemiology of Echovirus 30 in Taiwan, 1988–2008.

in Social Sciences Citation Index(SSCI), 社會科學引用文獻索引資料庫(SSCI)
標題Molecular epidemiology of Echovirus 30 in Taiwan, 1988–2008.
出版類型SSCI(Social Sciences Citation Index)
AuthorsGuan-Ming Ke, 柯冠銘, 林貴香, 盧柏樑, 董宜青, 柯良胤, 李敏生, & 褚珮瑜
出版日期2011 / 4

To investigate the molecular epidemiology of Taiwanese Echovirus 30 (E-30) strains, we analyzed the 876 bp sequence of the VP1 gene from 32 Taiwanese strains isolated in 1988–2008, 498 reference sequences, and one Echovirus 21 strain as the out-group. Phylogenetic analysis detected six E-30 genotypes (designated GI-GVI) that had circulated globally during the past five decades. The genotypes varied widely in geographic distribution and circulation half-life. The GI, GII, and GV were ancient genotypes in which the first strains emerged in the 1950s. The GIII was a reemerging genotype, in which strains had first appeared in Colombia in 1995 before reemerging in the New Independent States (NIS) in 2003. The GIV, an emerging genotype that recently appeared in Asia in 2003, was closely related to the ancient genotypes. The GVI was the circulating genotype, which included eight clusters (A–H) that had circulated since 1967. No GVI-A, C, D, or E strains have been identified during the past 10 years. The GVI-B first appeared in China in 1984 and later in Russia and Asia in the 2000s. The GVI-F, G, and H strains, which comprised the prevalent clusters, had been dominant in Asia Pacific area, globally, and Europe, respectively. Taiwanese strains were classified into GVI-D (1988–1989), GVI-F (1993–2004), and GVI-G (1993–2008). The quiescence period of E-30 is longer in Taiwan (5–8 years) than in other countries (3–5 years).

期刊名稱Virus Genes
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