Antioxidant capability of polysaccharides fractionated from submerge-cultured Agaricus blazei mycelia

in Sciences Citation Index(SCI), 科學引文索引資料庫(SCI)
標題Antioxidant capability of polysaccharides fractionated from submerge-cultured Agaricus blazei mycelia
出版類型SCI(Sciences Citation Index)
AuthorsYaw-Bee Ker, 柯耀筆, Kuan-Chou Chen K. - C. C., Charng-Cherng Chyau 喬長誠, Chin-Chu Chen C. - C. C., Jia-Hsin Guo 郭嘉信, Chiu-Lan Hsieh 謝秋蘭, Hui-Er Wang 王惠娥, Chiung-Chi Peng C. - C. P., Chi-Huang Chang 張基煌, & Robert Y. Peng 彭耀寰
出版日期2005 / 9

Five polysaccharide fractions (AB-1, AB-2, AB-3, AB-4, and AB-5) were obtained after a systemic solvent extraction and precipitation of Agaricus blazei mycelia with yields of 5.20, 9.03, 2.84, 17.47, and 0.44%, respectively. Among which, AB-1 and AB-3 demonstrated great DPPH* radical scavenging ability around 85.0 and 72.0%, respectively, at a concentration of 5 mg/mL. The ferrous ion chelating powers were even more excellent at a concentration of 1 mg/mL, reaching almost over 99.65% for fractions AB-2, AB-3, and AB-4 as compared to the reference control of citric acid (35%); at a dosage of 5 mg/mL, fraction AB-1 even showed 105% in efficiency. In terms of the absolute chelating power (ACIP), the mole numbers of ferrous (Fe2+) ions chelated were inversely related with the mean molecular mass of the polysaccharides in each fraction. In addition, gel permeation chromatography analysis showed that the more potent fractions were residing in those fractions with lower molecular masses, such as fractions AB-1 (757 kDa), AB-2 (887 kDa), and AB-4 (631 kDa) etc., and surprisingly, the free radical scavenging capability was also not closely correlated with the mean molecular masses, alternately being well-associated with the solubility of polysaccharides.

期刊名稱Journal of Agricultural and Food Chemistry
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